Characteristics of bone filling mesh container for treating osteoporotic vertebral compression fractures in older adults

doi:10.3969/j.issn.2095-4344.0768

Abstract

Abstract:

BACKGROUND: A bone filling mesh container in the treatment of vertebral compression fractures can not only effectively restore vertebral body height and biomechanical function, but also obviously reduce the leakage of bone cement and improve the success rate of surgery. Therefore, this method has aroused great attention in the current tissue engineering research and in the treatment of vertebral compression fractures.

OBJECTIVE: To evaluate the clinical effect of bone filling mesh container in the treatment of osteoporotic vertebral compression fractures in the older adults.

METHODS: Thirty cases of senile osteoporotic vertebral compression fractures were prospectively analyzed. Patients aged 56-78 years presented with single segmental vertebral compression fractures and underwent bilateral percutaneous kyphoplasty with the implantation of bone filling mesh container followed by bone cement injection. We detected visual analogue scale score, percentage of the elevation of the middle and anterior vertebral bodies, posterior Cobb’s angle and Oswestry dysfunction index score at postoperative 1 day, 1 week, 1 month and 6 months, respectively.

RESULTS AND CONCLUSION: All 30 patients completed the operation without bone cement leakage. After treatment, the visual analogue scale score, posterior Cobb’s angle and Oswestry dysfunction index score were significantly lowered in all patients (P < 0.05). However, there was no difference in the percentage of the elevation of the middle and anterior vertebral bodies at different time points after treatment. To conclude, the use of bone filling mesh container can obviously relieve patient’s pain, improve vertebral body height and protrusion deformity, and meanwhile significantly reduce bone cement leakage in patients with senile osteoporotic vertebral compression fractures.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Kyphoplasty, Osteoporotic Fractures, Tissue Engineering

CLC Number:

R318

Huang Hao-ran, Feng Li, Liang Hua, Feng De-wei, Teng Xue-ren, Yu Hua. Characteristics of bone filling mesh container for treating osteoporotic vertebral compression fractures in older adults[J]. Chinese Journal of Tissue Engineering Research, 2018, 22(26): 4110-4115.

Figures/Tables 3

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